Traditionally used for the symptomatic treatment associated with venous insufficiency and varicose veins.
The active ingredients of Horse Chestnut seeds are triterpene saponines (about thirty) collectively known as aescine or escine. Aescine increases vein wall resistance and reduces permeability (seepage), objectively reducing venous insufficiency symptoms (edema, swelling, etc.). Horse Chestnut seed extract is known for its phlebotonic, antioxidant, anti-inflammatory and vein wall protector effects.(1) It inhibits elastase and hyaluronidase activity. These two enzymes degrade the vein wall and the surrounding tissues (like collagen) therefore increasing venous insufficiency symptoms and progression (like spider veins, varicose veins and hemorrhoids).(2)
In vitro, aescine has demonstrated an anti-inflammatory effect.(3)
Horse Chestnut seed cannot reverse varicose veins.(4) Its effect is limited to symptom control and a slowing down of the disease progression, translating in an increased quality of life.
The German Commission E acknowledges its benefits in cases of: treatment of complaints found in pathological conditions of the veins of the legs (chronic venous insufficiency), for example, pains and a sensation of heaviness in the legs, nocturnal systremma (cramps in the calves), pruritis and swelling of the legs.
1 g of Venaforce Gel contains:
Medicinal ingredient:
Dry extract of Fresh Horse Chestnut (Aesculus hippocastanum) ...54 – 117 mg(DER 5.0 – 6.1:1, QDE: 270 mg – 714 mg) standardized to 2% aescin.
Non-medicinal ingredients:
water, alcohol, hypromellose, polyglyceryl-4 caprate, glycerine.
For external use:
Adults: Apply sparingly on legs 2 to 3 times daily. Avoid rubbing.
Always massage the legs upwards toward the heart to promote venous return.
Duration: Consult a healthcare practitioner for use beyond 6 weeks.
A 6 week treatment - 2 week pause cycle is suggested.
For external use only.
Avoid contact with eyes and mucous membranes.
Wash hands thoroughly after use.
Do not apply to inflamed skin or open wounds.
Do not use if you are pregnant or breastfeeding.
Avoid taking in case of allergy to any of the ingredients in the product.
Do not use if safety seal is broken. Keep out of the reach of children.
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